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In fact, the absorption of B12 requires that you have adequate stomach acid (among many other factors), which means that if you are taking acid blockers for reflux you are likely reducing your absorption of B12

These informal reports propose a potential daily dosage ranging from 50mg to 150mg

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PMC 1714280

On a standard 100-unit insulin syringe, 1 mL equals 100 units, so: 250 mcg dose = 10 units on the syringe 300 mcg dose = 12 units 500 mcg dose = 20 units Your prescribing physician or pharmacy will provide the exact calculation for your specific vial concentration and prescribed dose