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In particular, the oxidation state of two out of six cysteines controls the CAC via the formation of a disulfide bridge that switches off the transporter activity
In one study, the efficacy (as an antidote) of SAMe and NAC were comparable when given to mice within one hour of acetaminophen overdose (Terneus 2008)
In a systematic review and network meta-analysis, Zhang et al
Additional information Peer review information Nature Communications thanks Rumiana Dimova, Ziliang Zhao, and other, anonymous, reviewers for their contributions to the peer review of this work
Current notable studies focus on its potential in treating infected or injured eyes, such as cases involving Pseudomonas aeruginosa -induced keratitis, and the facilitation of corneal wound healing [5, 6]
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