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metformin)

1-10 mg/kg in animal studies KPV studies: 100 micromolar oral concentrations in colitis models

Uncommon and rare adverse effects include cystitis, folliculitis, gastrointestinal infections, hypersensitivity reactions, changes in appetite, depression, insomnia, balance disorders, lethargy, restless leg syndrome, syncope, photophobia, presbyopia, tinnitus, confusion, palpitations, hypertension, hypercholesterolaemia, and weight gain

Storage after reconstitution Reconstitution transforms a stable, shelf-stable powder into a perishable liquid

The molecule has a very high affinity for copper (II) and forms the chelate GHK-Cu