When combined with caloric restriction: the same study's diet-plus-injection arm showed 3.2 kg (7 pounds) additional loss versus diet-plus-placebo at 12 weeks, which was statistically significant (p=0.03)
Typically, to begin with, you'll be asked to take the injection multiple times a week to increase the B12 levels
Its research profile makes it especially relevant for studies focused on fat-cell pathway models, metabolic turnover, energy-balance signaling, methylation-adjacent biology, and body-composition pathway research
It has been studied for roles in actin binding, cell movement, angiogenesis, inflammation modulation, and wound healing
The GI side effects are present but manageable