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It is a type of melanocytic tumor that contains nevus cells
All findings remain investigational and confined to research environments
The intensity of the pain is similar to that of a sunburn
The molecule retains the complete 70-amino-acid native IGF-1 sequence with two structural modifications a 13-amino-acid N-terminal extension (the Long designation) and an arginine-for-glutamic-acid substitution at position 3 (the R3 designation) which together reduce binding affinity to circulating IGF binding proteins (IGFBPs) by approximately 600-fold while preserving full agonist activity at the IGF-1 receptor
Statistical analysis performed with two-way ANOVA followed by Tukey multiple-comparisons post-test ( d ), two-tailed unpaired t-test ( k,l ) or Benjamini-Hochberg ( e,i )
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