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Gowland Hopkins did further work on the substance in 1921

World J Gastroenterol 2011

This research positions gastrointestinal and oral chemosensors as a novel and non-invasive therapeutic target for managing metabolic syndrome and cognitive decline, overcoming the limitations of systemic bioavailability. Bitter compounds in plant foods have known health benefits, but the mechanisms underlying their effects in the body are still not fully understood

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