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GLP-1 users gained more weight and faced higher risks In the current study, 448 women who had previously been treated with GLP-1 RAs were compared to 1,344 controls

The increased risk was seen even after accounting for reflux disease, which is already known to be more common on GLP 1 drugs

In the PIONEER clinical trials, once-daily oral semaglutide demonstrated better efficacy compared to placebo, sitagliptin, empagliflozin, liraglutide, and dulaglutide in reducing cardiovascular risk [12]

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Konopleva M, Contractor R, Ruvolo P, Deng X, Samudio I, Shi Y, McQueen T, Wang R, Schober W, Ling X, Marini F, Harris D, Estrov Z, McCubrey J, May W, Andreeff M