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Apovian said her specialized practice has one employee managing prior authorizations and other paperwork for their eight practitioners and described the workload as overwhelming. That burden is going to be only greater for an independent physician practicing on their own
Most patients notice early changes within 4 to 8 weeks, with more meaningful improvements in pain and function between 3 and 6 months
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Moreover, every effort was made to minimize uncertainty in the analysis, by using an extensively published and validated health economic model, by utilizing clinical input data from published studies and by performing a series of extensive sensitivity analyses that demonstrated the outcomes of the base case analyses were robust [9, 10, 17,18,19]
B 124 , 23712381 (2020)
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