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Study-related adverse events Adverse reactions reported in 5% of patients and occurring more frequently with Victoza compared with placebo included nausea (21.4% vs 4.4%), vomiting (12.1% vs 2.2%), diarrhea (7.1% vs 2.9%), constipation (5.7% vs 1.5%), increased lipase (15.0% vs 8.8%), GFR decreased (6.4% vs 5.1%), and headache (5.0% vs 2.9%)

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with a BMI of 30 or more and heart failure with preserved ejection fraction, uncontrolled hypertension, or chronic kidney disease stage 3a or above

By activating MC3R and MC4R melanocortin receptors in the hypothalamus, it influences sexual desire and arousal through central nervous system pathways

These work by absorbing water and increasing faecal mass, stimulating peristalsis