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These symptoms are typically most pronounced during the initial weeks of treatment, the first 24hr-48hrs after the injection and when dosages are increased

Based on the trends throughout the past 4 decades and the changing chemical space in drug development, we expect the decade will show additional and significant current growth in use of solubilization technologies once we have visibility into the full 10-year period

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Gradual dose escalation, where the dosage is slowly increased, can help minimize this side effect, allowing the body to adjust more comfortably