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that combination has never been tested in humans

A bacterial laccase enzyme, CotA, has been shown to directly oxidize AFB1 into less toxic metabolites, namely aflatoxin Q1 (AFQ1) and epi-AFQ1, without the need for additional redox mediators

124 Domain A is the most highly conserved, whereas the B and C domains are more variable

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The nanoparticles of silibinin exhibited antioxidant effects against intracellular oxidative stress by upregulating the Nrf2/ARE pathway, reducing ROS, modulating antioxidant enzyme responsiveness, and inhibiting downstream pathways of mitochondrial damage (Ding et al., 2022)