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Sun et al, 2022

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WittemansLBLLottaLAOliver-WilliamsCStewartIDSurendranPKarthikeyanSet alAssessing the causal association of glycine with risk of cardio-metabolic diseases

The increased FAO driven by carnitine leads to an increase in intracellular acetyl-CoA levels, which can be transferred to the nucleus for acetylation of histone H3K27, thereby activating GATA3 gene expression and promoting the differentiation of triple-negative breast cancer cells to the luminal cell state [36]

Thereafter, the recombinant form of human growth hormone (rhGH) became available in unlimited quantities