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Patients with pre-existing diabetic retinopathy should have appropriate ophthalmologic follow-up

Changes in systolic and diastolic blood pressure showed no significant difference between the LC and CT groups

The TRIUMPH cardiovascular outcomes trial will determine whether these surrogate marker improvements translate to fewer actual cardiovascular events

When to seek specialist input: Inadequate response to first-line pharmacotherapy after 6 months Complex medical history (cardiovascular disease, psychiatric conditions) BMI 40 kg/m or 35 kg/m with significant comorbidities Considering any off-label or combination treatment Patient safety advice: Always discuss treatment options with your GP or obesity specialist before making changes

Comparing the 10 mg vial to other semaglutide sizes The 10 mg vial is not the only option