The American Journal of Psychiatry, 152 (5), 792794
SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis
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Furthermore, it presents, at position 20, a C20 fatty acid chain attached via a linker to the lysine residue, which enables the molecule to bind circulating albumin with high affinity, thus increasing the half-life up to 5 days (39), allowing a single weekly subcutaneous administration