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All experiments were conducted in a buffer solution containing 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM dithiothreitol (DTT), and 5% dimethyl sulfoxide (DMSO)

When the NNMT enzyme is overactive, its often associated with insulin resistance, a condition where your cells dont respond well to insulin and cant easily take up glucose from your blood

Over time, insulin resistance can lead to further complications, including impaired glucose tolerance, type 2 diabetes, and cardiovascular disease

Many patients experience improvement in post-inflammatory pigmentation and acne marks

Body composition: Those with higher body fat percentages may need different dosing considerations