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According to a recent study [25], enterocytes are the main target cells of SARS-CoV-2 and they respond to the infection by triggering a powerful inflammatory response

doi:10.3390/ph17040461

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doi: 10.1039/c5cc03301b 25 GonzlezA.SabioL.HurtadoC.Ramrez-RodrguezG

A phase 3 trial to test the benefits of melatonin treatment in association with hypothermia in infants with HIE was withdrawn prior to enrollment in 2015 (NCT01904786)