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The SURMOUNT-4 trial assessed the weight maintenance with tirzepatide and had also two periods: a 36-week open-label lead-in period during which all participants took tirzepatide, followed by a 52-week double-blind treatment period during which participants were randomised to either continue on tirzepatide or switch to placebo
Decreased levels of glutathione and elevated oxidative stress markers were observed in both siRNA (Fig
Strength and Conditioning Journal 43(4):p 53-61, August 2021
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