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Vuilleumier S (1997)
1 A few key points for clinicians: Short half-life (1012 min): This quick clearance supports physiologic GH pulses rather than continuous stimulation. Preserved feedback loops: IGF-1 and somatostatin feedback acts to keep GH levels within physiologic norms
The findings are encouraging: placental exosomes help regulate immune responses and support metabolic changes during pregnancy, while MSC-derived exosomes aid in wound healing and inflammation reduction - benefits that extend far beyond childbirth
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The observation that the induced effect on insulin secretion is different when oral glucose was administered versus the same amount of glucose parenterally coined the term incretin effect, supporting the idea that some substances secreted in the intestines favored the release of insulin after ingestion [1]
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