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Retatrutide is an investigational triple agonist peptide currently under clinical development, targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously

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Tirzepatide, for example, can result in significant weight loss over several months, while HCG injections may promote faster weight loss when paired with a low-calorie diet

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The FGF19 analog resulted in a substantial reduction in hepatic fat and enzymes in patients with biopsy-confirmed MASH, as shown in a phase 2A study