Simpson regards these treatments as reasonable things we can do to [increase] our health span and life span. Jeremie Walker, M.D., Dr
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The peptide influences both endothelial nitric oxide synthase (eNOS), which produces the beneficial, vasodilating form of nitric oxide, and inducible nitric oxide synthase (iNOS), which can produce excessive amounts that contribute to inflammation and tissue damage
The peptide was originally identified as a partial sequence derived from a larger protein present in human gastric juice, first characterized by Professor Predrag Sikiric and colleagues at the University of Zagreb, Croatia, in the early 1990s
Its much less potent than GLP-1s, but the muscle-sparing effect is important, as one-third of the weight lost on GLP-1s is muscle mass