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The health care provider usually considers a few things before recommending an appropriate vitamin B12 dosage: your diet and current medical condition

Rotating sites systematically allows any irritation to resolve before returning to a previously used location

Acute tryptophan depletion enhanced gastric accommodation, which was also observed with short-term SSRI use, while acute intravenous SSRI administration inhibited accommodation, suggesting that endogenous serotonin release serves to limit gastric accommodation (8284)

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