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Start Your Evaluation Safety Comparison: Side Effects and Contraindications Both medications have significant side effect profiles, but the nature of those side effects differs dramatically: Semaglutide side effects are primarily gastrointestinal: nausea (44%), diarrhea (30%), constipation (24%), and vomiting (24%)

Skipping meals can disrupt blood sugar levels, leading to insulin spikes and increased cortisol production, putting more stress on the already depleted adrenal gland system

The physician-supervised program feels safe and effective

Mitochondrial glutathione depletion can lead to premature cell death and accelerate the aging process

Some continue a low maintenance dose long-term