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He and other researchers worked for more than a decade to duplicate the effects of exendin-4, mostly because early iterations of GLP-1s were quickly broken down by the human body

Patients who stop the medication typically do not regain lost kidney function

It contributes to cardiac ischemia, hypertension, and diabetes by interacting with reactive oxygen species in cellular organelles

Blood Sugar Swings In people with diabetesor those prone to reactive hypoglycemiaGLP-1 medications can cause: Rapid glucose shifts Subtle hypoglycemia Low or rapidly falling blood sugar often presents as: Irritability Anxiety Short temper Feeling on edge Patients may not recognize this as a blood sugar issue, especially if they are not using continuous glucose monitoring