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Vitamin B12, unlike other Vitamin B members, is stored in the liver in significant amounts and is primarily found in animal-based foods
Taking it on an empty stomach in the morning exploits the lower gastric pH present after overnight fasting
But they were designed for insulin, not peptides, and this creates a translation challenge that confuses many researchers
You should get B12 shots weekly to monthly for maintenance and IV infusions monthly to quarterly for broader wellness support, though frequency depends on deficiency severity, health goals, and your providers recommendation
Why it matters: For patients with chronic joint pain, tendonitis, gut inflammation, or post-surgical inflammation, this means less swelling, better circulation, and faster repair
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