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This group of laxatives can therefore lead to melanosis coli, an increase in fat in the submucosa, atrophy of "smooth muscle and damage to intrinsic innervation.When there is a predominance of these last two aspects, the function of the large intestine is altered, as discussed elsewhere.The evidence of melanosis coli on a patient must immediately pose the problem on the harmful use of laxatives and symptoms of faecal stasis.In the absence of a history of abuse of anthraquinone laxatives, the finding of melanosis coli it requires further evaluation for the investigation of malignant neoplasm of the large intestine.

Oxidative stress is linked to several diseases, including heart disease, cancer, and arthritis

Post-Inflammatory Hyperpigmentation (PIH) PIH can occur after inflammation or injury to the skin

Operations of Novo Nordisk Inc., said in a statement sent to Fox Business

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