Regulation of glutathione in oxidative stress and cellular response mechanisms
Additionally, epicatechin ( 19 ), a starter unit for proanthocyanidins 33 , is produced cytosolically from cyanidin ( 8-AH + ) by the enzyme anthocyanidin reductase (ANR) (Extended Data Fig
96,97 Moreover, the ME1 protein is hypophosphorylated at S336 and hyperacetylated at K337 by PGAM family member 5 and acetyl-CoA acetyltransferase, respectively, resulting in ME1 translocation from mitochondria to the cytosol, dimerization and activation, thus strongly promoting NADPH generation and tumorigenesis
Sort of just found my passion and the answers I had been looking for with this new specialty finally after years of treating people with the Band-Aid fix it when its broken mentality instead of at the root cause. Mike has spent the last 10 years in Anti-Aging, Functional and Regenerative Medicine
But they follow completely different paths