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Since cancer continues to be a leading cause of death and disability, this is a significant additional potential benefit of GLP-1s
market as an obesity treatment
Gastrointestinal Function Studies Ipamorelins ghrelin-mimetic properties have been studied in gastrointestinal motility research: Dose-dependent improvement in gastric emptying in rodent postoperative ileus models Enhanced gastrointestinal contractility through cholinergic neuron activation Accelerated recovery of bowel function in experimental surgical models Effects mediated through ghrelin receptor activation in enteric nervous system Phase II human trials investigated ipamorelin for postoperative ileus treatment, though results did not reach statistical significance for primary endpoints
10.1016/j.cryobiol.2022.11.238 257
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