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Morroniside, a GLP-1R agonist, reduced mechanical allodynia and thermal hyperalgesia in a dose-dependent manner in a rat model of neuropathic pain, with peak effects within 1 h and lasting over 4 h [38]

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Bone Density: Mouse model studies have also linked IGF-1 signaling to improvements in bone density and skeletal strength, suggesting systemic health benefits beyond just muscular development