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Older options in the same class include liraglutide (Saxenda), although this is less commonly prescribed than the newer weekly injections

These agents work on brain reward pathways and appetite regulation systems that may be dysregulated in BED

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IGFBPs can also act to guide IGF-1 to specific tissues, or even to inhibit or potentiate IGF-1 actions by acting as an independent substrate for the IGF-1R and/or other specific membrane, intracellular or nuclear receptors [7]

The most common cause is Hashimoto's thyroiditis, an autoimmune disease in which your body attacks your thyroid gland