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10.1038/s41467-018-03465-9 17 De TenderC.DevrieseL
Brimonidine reduces production and increases outflow plus possible neuroprotective effects
Its mechanism is strictly enzymatic (NNMT inhibition)
Can GLOW and KLOW be used together in research
What that looks like in practice: some people notice shifts in energy and how their body composition responds before the scale moves much, since the goal is metabolic, not just water weight
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