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These changes are secondary to weight loss and improved glycemic control rather than direct lipid-lowering effects

It works by mimicking the effects of the hormone GLP-1, which helps to increase insulin secretion, reduce glucagon secretion, and slow gastric emptying, thereby improving blood sugar control and promoting weight loss

Wong, X

Advanced molecular studies reveal that FOXO4-DRI promotes p53 nuclear exclusion and subsequent mitochondrial targeting, where p53 interacts with BCL-2 family proteins to promote mitochondrial outer membrane permeabilization and cytochrome c release

Studies have shown fewer heart attacks and strokes in patients using GLP-1 receptor agonists