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Eating ice cream over 30 minutes has been shown to produce a significantly higher GLP-1 level compared to eating ice cream over five minutes
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[122] [123] Archaea [edit] In 2022, the discovery of serotonin N-acetyltransferase (SNAT) the penultimate, rate-limiting enzyme in the melatonin biosynthetic pathway in the archaeon Thermoplasma volcanium [124] firmly places melatonin biosynthesis in all three major domains of life, dating back to ~4 Gya
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