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In a recent study that included 48 patients 19 were treated with 50 mg/day pyridoxine hydrochloride and 22 with placebo, no statistically significant differences were found between the two groups (72)

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The products were determined by LC-MS/MS with d 4 -choline and 13 C 3 , 15 N-TMA added as internal standards and normalized to mass of fecal content