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This medicine may cause serious allergic reactions, including anaphylaxis and angioedema

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Unlike sodium-glucose cotransporter-2 (SGLT-2) inhibitors a separate class of diabetes medication associated with an increased risk of genital mycotic infections (such as thrush) and, to a lesser and more variable extent depending on the individual agent, urinary tract infections retatrutide does not act on the kidneys in a way that would be expected to directly predispose individuals to urinary infections

Furthermore, heritability estimates range from 30 to 40% (Girgenti et al., 2021) with genome-wide studies implicating immune-linked loci such as ANKRD55 among others (Stein et al., 2016

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