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Zinc dysregulation within the endolysosomal system also intersects with cancer biology: the alcohol-deterrent and emerging anticancer agent disulfiram disrupts endolysosomal structure and raises intraluminal zinc in breast cancer cells, implicating zinc dysregulation in its cytotoxicity and suggesting that extracellular zinc availability modulates its efficacy 169
10.1016/j.neuron.2008.07.033 19 ChooM.MiyazakiT.YamazakiM.KawamuraM.NakazawaT.ZhangJ.et al (2017)
8/ Who might benefit from tirzepatide for sleep apnea
However, maturation of erythrocytes and conversion of erythroblasts to mature erythrocytes during erythropoiesis is accompanied by enucleation and organelle clearance [32]
