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Nevertheless, in some instances a worsening of depressive symptoms may occur as a consequence of weight loss (well documented in series of bariatric surgery patients) and/or as a possible side effect of GLP-1 receptor agonist therapy. Before taking these drugs, make sure your healthcare provider knows about any mental health diagnoses or concerns you have and any medications you take

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Still, neither peptide is approved for cosmetic use, and neither is considered particularly safe when acquired outside of a medical setting

Berberine is found in plants and studies found people who took it saw decreases in body weight and BMI