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Spleens from MSK1/2 (serine/threonine kinase)-deficient mice accumulate eryptotic erythrocytes, and their erythrocytes are characterized by enhanced eryptosis following glucose depletion or hyperosmotic shock [152]

It has long been associated with diabetes and vascular issues, which is likely why researchers were investigating whether GLP-1 medications widely used to treat type 2 diabetes had any impact on its occurrence

We found that both male and female Tmprss2 / mice had increased ghrelin-encoding Ghrl mRNA levels in the stomach compared with WT mice (Figure 2L), indicating that post-transcriptional mechanisms primarily determine the significantly higher ghrelin levels in Tmprss2 / mice