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Re-evaluating the concept of remission in type 2 diabetes: a call for patient-centric approaches

These structural adaptations enhance molecular stability and allow for prolonged receptor engagement in laboratory models, making it suitable for studying sustained intracellular signaling compared to shorter-acting incretin analogs

On the other hand, beyond its acute insulinotropic effects, GLP-1 promotes -cell proliferation and inhibits apoptosis (Liu Y

Tirzepatides success proved that engaging both receptors simultaneously could produce effects greater than the sum of their parts

Clinicians must track glycemic control, manage side effects, and ensure proper medication use