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The recommended daily intake of B12 is between 2.4 and 2.8 mcg, but its low absorption rate is the reason for such high dosages in supplements (NIH, 2020)
One molecule plays a central role in all of these processes: NAD+ (nicotinamide adenine dinucleotide)
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Studies confirm that 5-Amino-1MQ treatment significantly reduces intracellular levels of the NNMT product 1-MNA while simultaneously increasing NAD+ and SAM concentrations in adipocytes and muscle cells
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