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Genome-wide analyses identify kif5a as a novel als gene

Activated microglia drive the immune response to the inflammatory state releasing immune signaling molecules (cytokines, and chemokines), and inducing neuronal cell death ( These data underline the importance of optimal glycemic control and call for major pharmacological interventions to reduce the risk of cardiometabolic-related cognitive impairment

Paone, P., et al

Improved mitochondrial efficiency has been observed, but prolonged caloric restriction may reduce mitochondrial biogenesis and oxidative capacity, compromising muscle function even if absolute mass loss is modest [35]

Han, H.S