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Isatuximab binds to the CD38 epitope via its gamma heavy chains, inducing cell death through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and apoptosis 146,147
Furthermore, elevation in ELF GSH levels was not arbitrary since the CS induced GSH adaptive response after a 3d exposure period prevented GSH levels from dropping below basal levels
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Other pathways proteins 17-HSD2 is a microsomal enzyme that catalyzes the oxidation of sex steroids testosterone and estradiol (E2) to less active ketones androstenedione and estrone (E1) 85,86
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