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FSH supports spermatogenesis by working with Sertoli cells to nurture developing sperm
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Oral formulations rely on passive absorption but, owing to the pathophysiology of the condition, patients with pernicious anaemia will only absorb around 1% of an orally administered dose[23]
However, it can also be given subcutaneously
Incidentally, the healthy reference range is 191-663 pg/ml and correlates closely with oral cobalamin intake, which is why the vitamin B12 blood level alone is not an adequate parameter to diagnose a deficiency (Herrmann and Obeid, 2014)
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