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Mol Biol Rep 2023;50:885566
In type 2 diabetes, the reduced expression of HO-1 will increase the production of ROS, leading to oxidative stress and inflammatory reaction, further aggravating cell damage (Table 2)
Figure 1 Figure 2 2 Apoptosis 2.1 Apoptotic signaling pathway Apoptosis, an RCD type that has been most widely investigated and precisely regulated, is featured by cell shrinking, plasma membrane blebbing, chromatin condensation, and apoptotic bodies formation (12, 100)
10.1038/srep18017 Sci
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