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Before a pen can be selected, the project team needs to understand: - Which API specification the project requires - Whether the formulation can support the intended concentration - How the API behaves in a 3ml cartridge route - Whether stability data can support the commercial plan - What documentation will be needed for buyer review - Whether supply can remain reliable beyond the first order The pen is visible to the end user
Analogous to rapamycin, tacrolimus (also known as TAC or FK506) demonstrates similar efficacy when incorporated with nanomaterials for treating ocular inflammation
The 12mg dose group in the Phase 2 trial had substantially more GI side effects than the 4mg group
Animals were caged together and treated in the same way
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