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Interestingly, recent studies have shown that melatonin is an important and essential hormone during pregnancy, specifically in the placenta
Originally isolated from human gastric juice, this 15-amino acid compound has been studied in preclinical animal models across multiple physiological systems.*1,9,10
Its a physiological process and NOT a sign of weakness or lack of willpower
These observations may partially explain why Nr1h2 -knockout mice exhibit lower plasma TG reductions in atherosclerosis models than Nr1h3- knockout mice 49 , further indicating the impact of LXR activity on the regulation of DNL and lipid metabolism 12,50
Yamada KM, Sixt M
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