In this review, we have relied on the interpretations provided by the original authors of the referenced studies while synthesizing the results, however, we acknowledge the limitations of these paradigms and the need for caution in their interpretation
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This occurs when the body retains excess fluid, leading to swelling in the extremities, particularly the hands, feet, and ankles
However, semaglutide produced substantial weight reduction without significantly higher dropout rates compared to other medications, suggesting a favorable benefit-risk balance