For B12, prolonged use of metformin and acid-suppressing drugs (PPIs, H2 blockers) may reduce absorption of oral B12, which is one reason injectable B12 is considered in select patients
Abbreviations SCI: Spinal cord injury NSCs: Neural stem cells AMPK: Adenosine 5-monophosphate-activated protein kinase Glutathione peroxidase 4: GPX4 SLC7A11: Solute carrier family 7 member 11 ACSL4: Acyl-coenzyme A synthetase long-chain family member 4 GSH: Glutathione ROS: Reactive oxygen species MMP: Mitochondrial membrane potential HE: Hematoxylin-eosin BBB: Basso, Beattie, and Bresnahan LSS: Louisville swim scale MEP: Motor evoked potentials References Huang H, Young W, Skaper S, Chen L, Moviglia G, Saberi H, Al-Zoubi Z, Sharma H, Muresanu D, Sharma A, et al
(PubMed) Aydin A, Ersoz G, Tekesin O, Akcicek E, Tuncyurek M
As this new melanin increases to protect our skin, there is an increase in hyperpigmentation, which represents damage to the skin from the sun
1 Both are informative and both were used in the AHK-Cu work