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32,37 Upon recognizing PAMPs and DAMPs, TLRs interact with adaptor molecules possessing a TIR domain, such as MYD88 innate immune signal transduction adaptor (MYD88) and TIR domain containing adaptor molecule 1 (TICAM1, also known as TIR domain-containing adaptor-inducing interferon- [TRIF])

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No upper limit restriction) - Prostatic specific antigen (PSA) (TRT is contraindicated for PSA equal or above 4.0) - Estradiol (Ultra-sensitive