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No systematic data exist regarding developmental safety, effects on linear growth and pubertal progression, or long-term cardiometabolic consequences in this population
Brief exposure above this threshold (a few hours in a hot car) may not destroy the medication, but repeated or prolonged heat exposure reduces potency
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During a Dose Increase If you are moving from a 2.5 mg dose to a 5 mg dose (or any other increase), you should not take the higher dose early
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