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We used the model to study the extent of liver damage caused by overdoses or by chronic use of therapeutic doses, and the effects of polymorphisms in glucoronidation enzymes

Of note, C1-27 inhibited the clonogenic survival of HCT116 cells at sub-micromolar concentrations (Fig

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Moreover, peroxisomes, organelles involved in lipid metabolism, contain enzymes such as acyl-CoA oxidase that generate hydrogen peroxide as a by-product [61]